Felbamate (hydrate)

Name	Felbamate (hydrate)
Synonyms	FelbaMate (hydrate) Felbamate (hydrate)
CAS	1177501-39-1

Molecular Formula	C11H16N2O5
Molar Mass	256.26
Solubility	10 mM in DMSO
Storage Condition	-20℃
In vitro study	Felbamate hydrate (W-554 hydrate) is an anti-epileptic drug used in the treatment of epilepsy. It is used to treat partial seizures (with and without generalization) in adults and partial and generalized seizures associated with Lennox-Gastaut syndrome in children. However, an increased risk of potentially fatal aplastic anemia and/or liver failure limit the drugs usage to severe refractory epilepsy. Felbamate (W-554) has been proposed to a unique dual mechanism of action as a positive modulator of GABAA receptors and as a blocker of NMDA receptors, particularly isoforms containing the NR2B subunit. Although it is clear that felbamate does cause pharmacological inhibition of NMDA receptor of relevance of NMDA receptor blockade as a strategy for the treatment of human epilepsy has been questioned. Therefore, the importance of the effects of felbamate on NMDA receptors to its therapeutic action in epilepsy is uncertain.

Product Name: Felbamate (hydrate) Visit Supplier Webpage Request for quotation
CAS: 1177501-39-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

Product Name: Felbamate (hydrate) Visit Supplier Webpage Request for quotation
CAS: 1177501-39-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

View History

Felbamate (hydrate)

Felbamate (hydrate) Request for Quotation